1 |
Description |
Colourless Crystals Or A White Crystalline Powder; Odourless And Bitter Taste. |
2 |
Solubility |
Freely Soluble In Water, Ethanol (95%), & Slightly Soluble In Diethyl Ether. |
3 |
Identification |
Test A May Be Omitted If Tests B, C &D Are Carried Out. Tests B, C And D May Be Omitted If Tests A Is Carried Out. A. Determine By Infrared Absorption Spectrophotometry. Compare The Spectrum With That Obtained With Nicotinamide RS Or With The Reference Spectrum Of Nicotinamide. B. Heat About 5 Mg In A Dry Tube; Pyridine Is Evolved. C. Boil 0.1 G With 10 Ml Of Dilute Sodium Hydroxide Solution; Ammonia Is Evolved. D. To 2 Ml Of A 0.1% W/V Solution Add 6 Ml Of Cyanogen Bromide Solution And 1 Ml Of A 2.5% W/V Solution Of Aniline; A Golden Yellow Colour Develops. |
4 |
Appearance Of Solution |
A 5% W/V Solution In Carbon Dioxide-Free Water Is Clear, And Not More Intensely Coloured That Reference Solution. |
5 |
Chloride |
Not More Than 250 Ppm. |
6 |
Sulphate |
1.2 G Complies With The Limit Test For Sulphates (125 Ppm). |
7 |
Related Substances |
Not More Than 0.2 %. |
8 |
Sulphated Ash |
Not More Than 0.1% |
9 |
Assay, W/W |
98.5 – 101.0% |
10 |
Heavy Metals |
Not More Than 30 Ppm |